Carlsmed® Reports Fourth Quarter and Full Year 2025 Financial Results
Carlsmed® Reports Fourth Quarter and Full Year 2025 Financial Results
February 25, 2026
Fourth quarter revenue of $15.2 million; 61% growth YoY
Full year revenue of $50.5 million; 86% growth YoY
CARLSBAD, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) -- Carlsmed, Inc. (Nasdaq: CARL) (“Carlsmed” or the “Company”), a medical technology company pioneering AI-enabled personalized spine surgery solutions, today reported financial results for the fourth quarter and full year ended December 31, 2025.
"We delivered another very strong quarter with 61% revenue growth year-over-year, gross margin expansion to 76.5%, and reduction of our lead times to within six business days. These achievements demonstrate our momentum and the speed at which we are scaling while maintaining our culture of patient-centric innovation,” said Mike Cordonnier, Chairman and CEO of Carlsmed.®
“With recent published data from a patient-matched cohort showing a 74% reduction in revision rates at two years for aprevo lumbar patients versus non-aprevo patients, we continue to advance our mission of improved outcomes and reduced cost of healthcare with a highly differentiated approach.”
Recent Business Highlights
- 2-year aprevo lumbar outcome data published in Global Spine Journal
- Launched aprevo cervical system
- Launched myaprevo ecosystem for browser and mobile integration
- First in-human aprevo bi-lateral posterior fusion procedure performed in February 2026 at University of Colorado
- First in-human personalized corra™ cervical plating procedure performed in February 2026 at UC San Francisco
Fourth Quarter 2025 Financial Results
- Revenue was $15.2 million for the fourth quarter of 2025, a 61.2% increase compared to $9.4 million for the fourth quarter of 2024
- Gross profit for the fourth quarter of 2025 was $11.6 million compared to $7.0 million for the fourth quarter of 2024. Gross margin was 76.5% for the fourth quarter of 2025, compared with 74.7% for the fourth quarter of 2024
- Operating expenses were $20.9 million for the fourth quarter of 2025, compared with $11.7 million for the fourth quarter of 2024, which consisted of:
- Research and development expenses of $5.3 million for the fourth quarter of 2025, compared with $3.0 million for the fourth quarter of 2024
- Sales and marketing expenses of $10.8 million for the fourth quarter of 2025, compared with $6.4 million for the fourth quarter of 2024
- General and administrative expenses of $4.9 million for the fourth quarter of 2025, compared with $2.3 million for the fourth quarter of 2024
- Net loss was ($8.6) million for the fourth quarter of 2025, compared to a ($4.7) million net loss for the fourth quarter of 2024
- Adjusted EBITDA was ($8.4) million for the fourth quarter of 2025, compared to ($4.6) million for the fourth quarter of 2024
- Cash and cash equivalents, restricted cash, and short-term investments were $109.9 million as of December 31, 2025
Full Year 2025 Financial Results
- Revenue was $50.5 million for 2025, an 86% increase compared to $27.2 million for 2024
- Gross profit for 2025 was $38.0 million compared to $20.0 million for 2024. Gross margin was 75.3% for 2025, compared with 73.8% for 2024
- Operating expenses were $68.6 million for 2025, compared with $44.2 million for 2024, which consisted of:
- Research and development expenses of $17.0 million for 2025, compared with $14.3 million for 2024
- Sales and marketing expenses of $35.0 million for 2025, compared with $21.5 million for 2024
- General and administrative expenses of $16.6 million for 2025, compared with $8.4 million for 2024
- Net loss was ($29.6) million for 2025, compared to ($24.3) million for 2024
- Adjusted EBITDA was ($28.4) million for 2025, compared to ($23.7) million for 2024
2026 Financial Outlook
- Revenue for 2026 is expected to be in the range of $70 to $75 million, representing growth at the midpoint of the range of 44% over 2025.
Non-GAAP Financial Measures
This press release contains certain financial information that is not presented in conformity with U.S. generally accepted accounting principles (“GAAP”), including Adjusted EBITDA. The non-GAAP financial measures are provided as supplemental information to Carlsmed’s financial measures presented in this press release that are calculated and presented in accordance with GAAP.
The Company calculates Adjusted EBITDA as net income (loss), as adjusted to exclude, as applicable, (i) net interest income (expense), (ii) income tax expense (benefit), (iii) depreciation expense from property and equipment (iv) amortization expense from long-lived assets, (iv) stock-based compensation expense and (v) change in fair value of warrant liabilities.
This non-GAAP measure is presented because management believes it allows investors to view the Company’s performance in a manner similar to the method used by management to evaluate financial performance for both strategic and annual operating planning. Management believes that to properly understand short-term and long-term financial trends, it is helpful for investors to understand the impact of the items excluded from the calculation of Adjusted EBITDA, in addition to considering the Company’s GAAP financial measures.
About Carlsmed
Carlsmed is a medical technology company pioneering AI-enabled personalized spine surgery solutions with a mission to improve outcomes and decrease the cost of healthcare for spine surgery and beyond.
CARLSMED, INC. CONDENSED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (in thousands, except share and per share amounts) (unaudited)
| Three Months Ended December 31, | Year Ended December 31, | |||
|---|---|---|---|---|
| 2025 | 2024 | 2025 | 2024 | |
| Revenue | $15,165 | $9,408 | $50,511 | $27,165 |
| Cost of sales | 3,557 | 2,384 | 12,471 | 7,117 |
| Gross profit | 11,608 | 7,024 | 38,040 | 20,048 |
| Operating expenses: | ||||
| Research and development | 5,264 | 3,015 | 17,019 | 14,304 |
| Sales and marketing | 10,809 | 6,380 | 35,027 | 21,472 |
| General and administrative | 4,853 | 2,326 | 16,568 | 8,394 |
| Total operating expenses | 20,926 | 11,721 | 68,614 | 44,170 |
| Loss from operations | (9,318) | (4,697) | (30,574) | (24,122) |
| Other income (expense): | ||||
| Interest expense | (330) | (378) | (1,430) | (1,321) |
| Interest income | 1,028 | 410 | 2,698 | 1,330 |
| Change in fair value of warrant liabilities | 7 | (55) | (328) | (144) |
| Total other income (expense), net | 705 | (23) | 940 | (135) |
| Net loss and comprehensive loss | (8,613) | (4,720) | (29,634) | (24,257) |
| Deemed dividend to preferred stockholders | - | - | (584) | (592) |
| Net loss attributable to common stockholders | $(8,613) | $(4,720) | $(30,218) | $(24,849) |
| Net loss per share attributable to common stockholders, basic and diluted | $(0.32) | $(1.14) | $(2.12) | $(6.11) |
| Weighted-average number of common shares used to compute basic and diluted net loss per share | 26,597,105 | 4,126,371 | 14,221,991 | 4,066,395 |
CARLSMED, INC. CONDENSED BALANCE SHEETS (in thousands, except for share and par value amounts) (unaudited)
| December 31,2025 | December 31,2024 | |
|---|---|---|
| Assets | ||
| Current assets: | ||
| Cash and cash equivalents | $85,793 | $40,125 |
| Restricted cash | 100 | 100 |
| Short-term investments | 24,000 | - |
| Accounts receivable, net of allowances of $1,653 and $1,239, as of December 31,2025 and December 31,2024, respectively | 11,362 | 6,766 |
| Inventory | 1,845 | 995 |
| Prepaid expenses and other current assets | 3,573 | 1,365 |
| Total current assets | 126,673 | 49,351 |
| Property and equipment, net | 1,487 | 260 |
| Operating lease right-of-use assets | 1,826 | 1,644 |
| Other assets | 134 | 569 |
| Total assets | $130,120 | $51,824 |
| Liabilities, Convertible Preferred Stock, and Stockholders' Equity (Deficit) | ||
| Current liabilities: | ||
| Accounts payable | $4,481 | $2,412 |
| Accrued liabilities | 3,287 | 2,687 |
| Accrued compensation | 5,760 | 3,270 |
| Short-term operating lease liabilities | 752 | 449 |
| Total current liabilities | 14,280 | 8,818 |
| Long-term portion of term loan, net | 15,346 | 15,414 |
| Long-term operating lease liabilities | 1,316 | 1,317 |
| Warrant liabilities | - | 457 |
| Other long-term liabilities | 309 | 222 |
| Total liabilities | 31,251 | 26,228 |
| Commitments and contingencies (Note 9) | ||
| Series A convertible preferred stock,$0.00001 par value; zero shares authorized, issued,and outstanding and zero liquidation preference as of December 31,2025;4,902,814 sharesauthorized, issued,and outstanding,and $13,767 liquidation preference as of December 31,2024 | - | 13,578 |
| Series B convertible preferred stock,$0.00001 par value; zero shares authorized, issued,and outstanding and zero liquidation preference as of December 31,2025;4,393,481 sharesauthorized,4,335,051 shares issued and outstanding,and $30,000 liquidation preferenceas of December 31,2024 | - | 29,801 |
| Series C convertible preferred stock,$0.00001 par value; zero shares authorized,issued,and outstanding and zero liquidation preference as of December 31,2025;4,910,500 sharesauthorized,4,890,123 shares issued and outstanding,and $52,500 liquidation preferenceas of December 31,2024 | - | 52,847 |
| Stockholders' equity (deficit): | ||
| Preferred stock,$0.00001 par value;10,000,000 shares authorized and zero shares issuedand outstanding as of December 31,2025;zero shares authorized,issued,and outstandingas of December 31,2024 | - | - |
| Common stock,$0.00001 par value;600,000,000 shares authorized,26,664,243sharesissued,and26,604,505 shares outstandingas of December 31,2025;21,835,801sharesauthorized,4,234,798 shares issued,and4,139,219 shares outstandingas of December31,2024 | - | - |
| Additional paid-in capital | 199,674 | 541 |
| Accumulated deficit | (100,805) | (71,171) |
| Total stockholders' equity (deficit) | 98,869 | (70,630) |
| Total liabilities,convertible preferred stock,and stockholders' equity(deficit) | $130,120 | $51,824 |
RECONCILIATION OF GAAP NET LOSS TO ADJUSTED EBITDA (unaudited)
| Three Months Ended December 31, | $ Change | % Change | |||
|---|---|---|---|---|---|
| 2025 | 2024 | $ Change | % Change | ||
| (in thousands, except percentages) | |||||
| Net loss | $(8613) | $(4720) | $(3893) | 82.5% | |
| Interest (income) expense, net | (698) | (32) | (666) | ||
| Income taxes | - | - | - | - | |
| Depreciation and amortization | 98 | 37 | 61 | 164.9% | |
| EBITDA | (9,213) | (4,715) | (4,498) | 95.4% | |
| Stock-based compensation | 790 | 100 | 690 | 690.0% | |
| Change in fair value of warrant liabilities | (7) | 55 | (62) | (112.7%) | |
| Adjusted EBITDA | $(8,430) | $(4,560) | $(3,870) | 84.9% | |
| Year Ended December 31, | $ Change | % Change | |||
| 2025 | 2024 | $ Change | % Change | ||
| (in thousands, except percentages) | |||||
| Net loss | $(29,634) | $(24,257) | $(5,377) | 22.2% | |
| Interest income, net | (1,268) | (9) | (1,259) | ||
| Income taxes | - | - | - | - | |
| Depreciation and amortization | 281 | 145 | 136 | 93.8% | |
| EBITDA | (30,621) | (24,121) | (6,500) | 26.9% | |
| Stock-based compensation | 1,927 | 253 | 1,674 | 661.7% | |
| Change in fair value of warrant liabilities | 328 | 144 | 184 | 127.8% | |
| Adjusted EBITDA | $(28,366) | $(23,724) | $(4,642) | 19.6% |